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touba: Illustration by Rachel Urkowitz for the cover of the February 2013 issue of The Journal of Experimental Medicine, based on the work of Yang et al., who “show that immune tolerance to self-antigens impedes the generation of some broadly protective antibodies that bind to HIV gp41. One self-antigen, kynureninase, is mutated in opossums, allowing these marsupials to generate high serum antibody titers to the corresponding HIV epitope. The cover image depicts a HIV virus (orange) with viral spikes containing gp41 subunits (blue) and Y-shaped antibodies (green).”  (source)
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touba:

Illustration by Rachel Urkowitz for the cover of the February 2013 issue of The Journal of Experimental Medicine, based on the work of Yang et al., who “show that immune tolerance to self-antigens impedes the generation of some broadly protective antibodies that bind to HIV gp41. One self-antigen, kynureninase, is mutated in opossums, allowing these marsupials to generate high serum antibody titers to the corresponding HIV epitope. The cover image depicts a HIV virus (orange) with viral spikes containing gp41 subunits (blue) and Y-shaped antibodies (green).”  (source)

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